Claes-Göran Östenson


Claes-Göran Östenson, M.D., Ph.D.
Department of Molecular Medicine and Surgery, Endocrine and Diabetes Unit Karolinska Institutet, Stockholm, Sweden

PhD (Doktorsexamen): 1979, Histology, Uppsala University.
Docent (Ass Prof): 1982 Medical Cellbiology (Uppsala), 1986 Endocrinology (Karolinska Institutet).

Present appointment:

Senior professor of endocrinology, Karolinska Institutet

Postgraduate and postdoctoral students: Supervised to doctoral dissertation16 postgraduate students as main supervisor and 9 students as co-supervisor. In addition supervised 2 postdoctoral student. At present, supervising 3 postgraduate students.

Scientific production

Published about 350 original papers in the field of diabetes research, i.e. on pathogenesis and treatment of type 2 diabetes including epidemiology, genetics, and studies in animal models of the disease:

  1. Novel therapy of type 2 diabetes by assessing anti-diabetic effects of traditional plant extracts, and isolated active compounds from such extracts, from Southeast Asian countries.
  2. Epidemiology and impact of risk factors in life style and humoral biomarkers, in a cohort of 8000 subjects in Stockholm, studied at baseline and follow-up after 10 years.
  3. Genetic studies, i.e. genotyping in the material described above, relating SNP´s to prediabetes, diabetes and obesity.
  4. Prevention of type 2 diabetes.
  5. Studies of mechanisms behind impaired B-cell function in man as well as in animal models of type 2 diabetes, e.g. the Goto-Kakizaki (GK) rat.

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